ZOTAROLIMUS

Chemical FDA Substance Registry (openFDA)

Learn more about this substance: Ask ChatGPT Google PubChem Wikipedia EWG Skin Deep INCIDecoder ECHA

Chemical Identification

CAS Number	`221877-54-9`
INCI Name	(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-12-[(2R)-1-[(1S,3R,4S)-3-methoxy-4-(tetrazol-1-yl)cyclohexyl]propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
PubChem CID	9876378
Molecular Formula	`C52H79N5O12`
InChIKey	`InChI=1S/C52H79N5O12/c1-31-`
SMILES	`C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@@H]([C@@H](C4)OC)N5C=NN=N5)C)/C)O)OC)C)C)/C)OC`

Known Aliases (6)

Common Name

ABT-578 MDT-4107 zotarolimus [INN] ZOTAROLIMUS [MART.] ZOTAROLIMUS [USAN] Zotarolimus [WHO-DD]

Data Sources (1)

Source	Source ID	Name in Source	Properties
FDA Substance Registry (openFDA)	`H4GXR80IZE`	ZOTAROLIMUS	CAS: 221877-54-9 INN: 8644 MESH: C489443 USAN: QQ-84 EVMPD: SUB32090 ChEMBL: CHEMBL1614661 SMS_ID: 100000124446 PUBCHEM: 9876378 FDA UNII: H4GXR80IZE WIKIPEDIA: Zotarolimus EPA CompTox: DTXSID50873387 DRUG CENTRAL: 2949 NCI_THESAURUS: C2201

Record Info

ID	`9rDnQj9WPZnKJN4yhqRmpa`
Created	April 10, 2026, 7:44 p.m.
Modified	April 11, 2026, 12:15 a.m.
Enriched	April 11, 2026, 12:09 a.m.
Data Source	FDA Substance Registry (openFDA)