Zodasiran

ADS-004 RNA, ([1′-de(6-amino-9H-purin-9-yl)]dA-(5′→5′)-sᵖ-Gm-Cm-Um-Cm-Am-Am-Cm-Am-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)U-Um-Um-Gm-Am-Um-Cm-Am-Gm-Um-Am-(3′→3′)-sᵖ-[1′-de(6-amino-9H-purin-9-yl)]dA), 3′-[O-[cis-4-[(3S,8S)-17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,8-bis[[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]-1,6,11-trioxo-15-oxa-2,7,12-triazaheptadec-1-yl]cyclohexyl] hydrogen phosphorothioate], complex with RNA (Um-sᵖ-(2′-deoxy-2′-fluoro)A-sᵖ-Cm-sᵖ-(2′-deoxy-2′-fluoro)U-Gm-(2′-deoxy-2′-fluoro)A-Um-(2′-deoxy-2′-fluoro)C-Am-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)U-Am-(2′-deoxy-2′-fluoro)U-Gm-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)G-Am-(2′-deoxy-2′-fluoro)G-sᵖ-Cm) (1:1) zodasiran [INN] ZODASIRAN [USAN]