Zabilugene Almadenorepvec
Chemical
FDA Substance Registry (openFDA)
Learn more about this substance:
Ask ChatGPT
Google
PubChem
Wikipedia
EWG Skin Deep
INCIDecoder
ECHA
Chemical Identification
| CAS Number | 2937327-18-7 |
|---|
Known Aliases (3)
Common Name
DNA (recombinant tumor-selective replicating oncolytic human adenovirus 5 vector VCN-01 transcription factor E2F-binding boxes plus transcription factor SP1-binding box-containing promoter 415 plus human adenovirus 5 gene E1A-Δ24 plus human hyaluronidase PH-20 soluble form-specifying)
KKTK domain of the fiber shaft with an integrin-binding, tumour-selectirecombinant, replication-competent oncolytic human adenovirus type 5 (Ad5) vector, encoding human hyaluronidase PH-20 (sperm adhesion molecule 1 [SPAM1] soluble form), under the control of the adenovirus major late promoter via insertion of the pIIIa splice acceptor and a Kozak sequence. Genetic modifications of the viral genome also include the insertion of four E2F-responsive sites along with one extra Sp-1 transcription factor binding site to control expression of the viral early region 1A (E1A) gene, a 24 base pair deletion in the E1A gene, and the replacement of the ve RGDK motif
zabilugene almadenorepvec [INN]
Data Sources (1)
| Source | Source ID | Name in Source | Properties |
|---|---|---|---|
| FDA Substance Registry (openFDA) | 3HBM7CA87P |
Zabilugene Almadenorepvec |
CAS: 2937327-18-7 INN: 13271 SMS_ID: 100000182774 FDA UNII: 3HBM7CA87P NCI_THESAURUS: C211709 |
Record Info
| ID | NZfbN36jGYScobmgXEVu5F |
|---|---|
| Created | April 10, 2026, 9:05 p.m. |
| Modified | April 10, 2026, 11:03 p.m. |
| Data Source | FDA Substance Registry (openFDA) |