Zegruvirimat

Chemical FDA Substance Registry (openFDA)

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Chemical Identification

CAS Number	`2122781-86-4`
INCI Name	(1S)-4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[2-(1,1-dioxo-1,4-thiazinan-4-yl)ethylamino]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]-1-[(3-cyano-2-pyridinyl)oxymethyl]cyclohex-3-ene-1-carboxylic acid
PubChem CID	130343923
Molecular Formula	`C49H70N4O5S`
InChIKey	`InChI=1S/C49H70N4O5S/c1-33(`
SMILES	`CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@H]4[C@]([C@@]3(CC2)C)(CC[C@@H]5[C@@]4(CC=C(C5(C)C)C6=CC[C@@](CC6)(COC7=C(C=CC=N7)C#N)C(=O)O)C)C)NCCN8CCS(=O)(=O)CC8`

Known Aliases (9)

Common Name

GSK-3739937 GSK3739937 VH-3739937 VH3739937 zegruvirimat [INN] ZEGRUVIRIMAT [USAN]

Scientific Name

(1S)-1-{[(3-cyanopyridin-2-yl)oxy]methyl}-4-[17-{[2-(1,1-dioxo-1λ⁶-thiomorpholin-4-yl)ethyl]amino}-28-norlupa-2,20(29)-dien-3-yl]cyclohex-3-ene-1-carboxylic acid 3-Cyclohexene-1-carboxylic acid, 1-[[(3-cyano-2-pyridinyl)oxy]methyl]-4-[17-[[2-(1,1-dioxido-4-thiomorpholinyl)ethyl]amino]-28-norlupa-2,20(29)-dien-3-yl]-, (1S)- (S)-1-(((3-Cyanopyridin-2-yl)oxy)methyl)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-((2-(1,1-dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)cyclohex-3-ene-1-carboxylic acid

Data Sources (1)

Source	Source ID	Name in Source	Properties
FDA Substance Registry (openFDA)	`4AN783M8MZ`	Zegruvirimat	CAS: 2570811-78-6 INN: 12118 USAN: MN-105 SMS_ID: 300000023132 PUBCHEM: 130343923 FDA UNII: 4AN783M8MZ NCI_THESAURUS: C190317

Record Info

ID	`V2TvnB3UAQmKisscZhW9s5`
Created	April 10, 2026, 9:31 p.m.
Modified	April 10, 2026, 11:11 p.m.
Enriched	April 11, 2026, 12:09 a.m.
Data Source	FDA Substance Registry (openFDA)