Zamubafusp Alfa

gamma 1 heavy chain (1-441) [VH (Homo sapiens IGHV4-4*08 -(IGHD) -IGHJ4*01, CDR-Kabat [5.16.3] (31-35.50-65.98-100)) (1-111) -Homo sapiens IGHG1*01 (CH1 (112-209), hinge (210-224), CH2 (225-334), CH3 (335-439), CHS (440-441)) (112-441)], (214-219')-disulfide with kappa light chain (1'-219') [V-KAPPA (Homo sapiens IGKV2-30*01 -IGKJ2*01, CDR-Kabat [16.7.9] (24'-39'.55'-61'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (113'-219')], fused via peptide linker ^220' VSPSV ^224' to the pan-amyloid-reactive peptide p5R (225'-250'), dimer (220-220'':223-223'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfaextracted ion chromatogram (EIC) ratio humanized immunoglobulin G1-kappa, anti-[human variable immunoglobulin light chain N-terminal cryptic neo-epitope] fused at the C-terminus of each light chain via a peptide linker to the pan-amyloid-reactive peptide p5R Immunoglobulin G1 [54-glutamic acid], anti-(human amyloid fibrils) (human-Mus musculus monoclonal VH9/VL4 γ1-chain), disulfide with [33-serine] human-Mus musculus monoclonal VH9/VL4 κ-chain fusion protein with pan-amyloid-reactive peptide p5R, dimer zamubafusp alfa [INN]