(αS,5α,7α)-(α′S,5′α,7′α)-17,17′-Bis(cyclopropylmethyl)-α,α′-bis(1,1-dimethylethyl)-4,5:4′,5′-diepoxy-18,18′,19,19′-tetrahydro-3,3′-dihydroxy-6,6′-dimethoxy-α,α′-dimethyl[2,2′-bi-6,14-ethenomorphinan]-7,7′-dimethanol

Chemical FDA Substance Registry (openFDA)

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Chemical Identification

CAS Number	`163597-04-4`
INCI Name	(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-10-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11-hydroxy-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8,10,12(20)-trien-10-yl]-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8,10,12(20)-trien-11-ol
PubChem CID	139468475
Molecular Formula	`C58H80N2O8`
InChIKey	`InChI=1S/C58H80N2O8/c1-49(2`
SMILES	`C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=CC(=C(C(=C56)O4)O)C7=C(C8=C9C(=C7)C[C@@H]1[C@@]23[C@]9(CCN1CC1CC1)[C@@H](O8)[C@@](CC2)([C@H](C3)[C@@](C)(C(C)(C)C)O)OC)O)CC1CC1)OC)(C(C)(C)C)O`

Known Aliases (8)

Common Name

6α,14-ethano-14α-morphinan Buprenorphine 2,2’-dimer BUPRENORPHINE HYDROCHLORIDE IMPURITY G [EP IMPURITY] BUPRENORPHINE IMPURITY G [EP IMPURITY] Pseudobuprenorphine

Scientific Name

17,17′-di(cyclopropylmethyl)-4,5α;4′,5α′-diepoxy-7α,7α′-di[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6,6′-dimethoxy-2,2′-bi 2,2’-Bi{17-(cyclopropylmethyl)-4,5α-epoxy-3-hydroxy-7α-[(S)-2-hydroxy-3,3-dimethylbutan-2-yl]-6-methoxy-6α,14-ethanomorphinan} [2,2′-Bi-6,14-ethenomorphinan]-7,7′-dimethanol, 17,17′-bis(cyclopropylmethyl)-α,α′-bis(1,1-dimethylethyl)-4,5:4′,5′-diepoxy-18,18′,19,19′-tetrahydro-3,3′-dihydroxy-6,6′-dimethoxy-α,α′-dimethyl-, [5α,7α(S)]-[5′α,7′α(S)]-

Data Sources (1)

Source	Source ID	Name in Source	Properties
FDA Substance Registry (openFDA)	`43MH6YYF5W`	(αS,5α,7α)-(α′S,5′α,7′α)-17,17′-Bis(cyclopropylmethyl)-α,α′-bis(1,1-dimethylethyl)-4,5:4′,5′-diepoxy-18,18′,19,19′-tetrahydro-3,3′-dihydroxy-6,6′-dimethoxy-α,α′-dimethyl[2,2′-bi-6,14-ethenomorphinan]-7,7′-dimethanol	CAS: 163597-04-4 PUBCHEM: 139468475 FDA UNII: 43MH6YYF5W EPA CompTox: DTXSID90858350

Record Info

ID	`iTWe8KUL3PCpfVqA2ftHVN`
Created	April 10, 2026, 8:37 p.m.
Modified	April 10, 2026, 11:38 p.m.
Enriched	April 11, 2026, 12:09 a.m.
Data Source	FDA Substance Registry (openFDA)