Zolbetuximab

Chemical FDA Substance Registry (openFDA)

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Chemical Identification

CAS Number	`1496553-00-4`

Known Aliases (9)

Common Name

CLAUDIXIMAB IMAB-362 IMAB362 Immunoglobulin G1, anti-(human claudin-18.2) (human-Mus musculus monoclonal IMAB362 heavy chain), disulfide with human-Mus musculus monoclonal IMAB362 κ-chain, dimer Immunoglobulin G1-kappa, anti-[Homo sapiens CLDN18 (claudin 18, claudin-18, SFTPJ, surfactant associated protein J) isoform 2, extracellular domain 1 (EC1)], chimeric monoclonal antibody; gamma1 heavy chain (1-448) [Mus musculus VH (IGHV1-61*01 (92.90%) -(IGHD) -IGHJ2*01) [8.8.11] (1-118) -Homo sapiens IGHG1*03, G1m3, nG1m1 (CH1 R120 (215) (119-216), hinge (217-231), CH2 (232-341), CH3 E12 (357), M14 (359) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with kappa light chain (1'-220') [Mus musculus V-KAPPA (IGKV8-19*01 (100.00%) -IGKJ4*01) [12.3.9] (1'-113') -Homo sapiens IGKC*01, Km3 A45.1 (159), V101 (197) (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide zolbetuximab [INN] ZOLBETUXIMAB [JAN] ZOLBETUXIMAB [USAN] Zolbetuximab [WHO-DD]

Data Sources (1)

Source	Source ID	Name in Source	Properties
FDA Substance Registry (openFDA)	`TF5MPQ8WGY`	Zolbetuximab	CAS: 1496553-00-4 INN: 10473 USAN: KL-138 CHEMBL: CHEMBL2109427 SMS_ID: 100000175835 FDA UNII: TF5MPQ8WGY DRUG BANK: DB15118 WIKIPEDIA: Zolbetuximab NCI_THESAURUS: C129822 FDA ORPHAN DRUG: 383312

Record Info

ID	`kodDnAmzhX5WSGpWLuyKgT`
Created	April 10, 2026, 8:54 p.m.
Modified	April 10, 2026, 11:04 p.m.
Data Source	FDA Substance Registry (openFDA)