(Z)-(S)-2-[3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Chemical FDA Substance Registry (openFDA)

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Chemical Identification

CAS Number	`1575598-09-2`
INCI Name	(Z)-2-[(3S)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile
PubChem CID	90004027
Molecular Formula	`C36H40FN9O3`
InChIKey	`InChI=1S/C36H40FN9O3/c1-36(`
SMILES	`CC(C)(/C=C(/C#N)\C(=O)N1CCC[C@@H](C1)N2C3=NC=NC(=C3C(=N2)C4=C(C=C(C=C4)OC5=CC=CC=C5)F)N)N6CCN(CC6)C7COC7`

Known Aliases (3)

Common Name

Rilzabrutinib, (αZ,3S)-

Scientific Name

1-Piperidinepropanenitrile, 3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-α-[2-methyl-2-[4-(3-oxetanyl)-1-piperazinyl]propylidene]-β-oxo-, (αZ,3S)- (αZ,3S)-3-[4-Amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-α-[2-methyl-2-[4-(3-oxetanyl)-1-piperazinyl]propylidene]-β-oxo-1-piperidinepropanenitrile

Data Sources (1)

Source	Source ID	Name in Source	Properties
FDA Substance Registry (openFDA)	`P9HMV9CG85`	(Z)-(S)-2-[3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile	CAS: 1575598-09-2 PUBCHEM: 90004027 FDA UNII: P9HMV9CG85

Record Info

ID	`kwBaCuGBdY7YpGXKdip72P`
Created	April 10, 2026, 10:39 p.m.
Modified	April 10, 2026, 10:39 p.m.
Enriched	April 11, 2026, 12:09 a.m.
Data Source	FDA Substance Registry (openFDA)